Modulation of calcium-binding proteins expression and cisplatin chemosensitivity by calcium chelation in human breast cancer MCF-7 cells
Cisplatin (CDDP) is currently one of the most effective FDA-approved treatments for breast cancer.Previous studies have shown that CDDP-induced cell death in human breast cancer (MCF-7) cells is associated with disruption of calcium homeostasis.However, whether the sensitivity of breast cancer cells to cisplatin is associated with dysregulation of